
der Tic
tic
An involuntary, quick, and repeated muscle movement or vocalization that is often caused by nervousness.
Er hat einen leichten Tic und zuckt manchmal mit dem Augenlid.
He has a slight tic and sometimes his eyelid twitches.
tic
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tic
An involuntary, quick, and repeated muscle movement or vocalization that is often caused by nervousness.
Er hat einen leichten Tic und zuckt manchmal mit dem Augenlid.
He has a slight tic and sometimes his eyelid twitches.

quirk
In a figurative sense, a strange habit or quirk that is typical of a person.
Es ist so ein Tic von ihm, dass er immer dreimal auf den Tisch klopft, bevor er das Haus verlässt.
It's a quirk of his that he always knocks on the table three times before leaving the house.
'Der Tic' (the tic) refers to an involuntary muscle movement or a quirk. It is not the English word 'tick', which refers to the sound of a clock, a check mark, or an insect ('die Zecke' — tick).
Sein nervöser Tic ist, ständig mit dem Fuß zu wippen.
His nervous tic is constantly bouncing his foot.
The most common way to talk about a tic is the phrase 'einen Tic haben' (to have a tic/quirk). This construction works for both meanings of the word.
Meine Kollegin hat den Tic, jeden Stift nach Farbe zu sortieren.
My colleague has the quirk of sorting every pen by color.
You can recognize the figurative meaning from the fact that it refers to a deliberate but strange action, not an uncontrollable muscle twitch. It is often described as a personal peculiarity.
Es ist ein Tic von meinem Opa, vor dem Essen immer an seinem Glas zu riechen.
It's a quirk of my grandpa's to always smell his glass before eating.
To describe a strange habit, the structure 'Es ist ein Tic von [person in the dative], dass ...' (It is a quirk of [person]'s that ...) is often used.
Es ist ein Tic von ihr, dass sie ihre Bücher immer nach der Größe ordnet.
It's a quirk of hers that she always arranges her books by size.
quirk / tic
Both words can refer to a conspicuous personal characteristic. In general usage, „Tick“ tends to mean a strange habit or quirk, while „Tic“ specifically emphasizes an involuntary, repeated movement or vocalization. „Tick“ is more appropriate for a conscious ritual, while „Tic“ is more appropriate for uncontrollable blinking.

Vor wichtigen Gesprächen hat sie den Tic, unwillkürlich immer wieder zu blinzeln.
Before important conversations, she has a tic that makes her blink repeatedly and involuntarily.
Vor wichtigen Gesprächen hat sie den Tick, ihre Notizen immer dreimal zu ordnen.
Before important conversations, she has the quirk of always arranging her notes three times.