die Bremse
brake
A technical device on a vehicle or machine used to reduce speed or bring it to a stop.
Vor der Kurve musste der Fahrer stark auf die Bremse treten.
Before the curve, the driver had to step hard on the brake.

brake / horsefly
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brake
A technical device on a vehicle or machine used to reduce speed or bring it to a stop.
Vor der Kurve musste der Fahrer stark auf die Bremse treten.
Before the curve, the driver had to step hard on the brake.

'Die Bremse' belongs to the word family of the verb 'bremsen' (to brake). The noun refers to the device, while the verb describes the action of reducing speed.
Du musst stärker bremsen, die Ampel ist rot!
You need to brake harder; the traffic light is red!
The three meanings can be distinguished well from context. If people are talking about vehicles or machines, the technical device is meant. In the context of nature and insects, the animal is meant. In discussions about economics or politics, the figurative meaning is meant.
Die Bremsen an meinem Fahrrad funktionieren nicht mehr richtig.
The brakes on my bicycle don't work properly anymore.
When talking about the brake in a car, the most common and natural phrasing is 'auf die Bremse treten' (to step on the brake). Here you use the verb 'treten' (to step), not 'drücken' (to press) or 'schieben' (to push).
Als ein Kind auf die Straße lief, trat der Fahrer sofort auf die Bremse.
When a child ran into the street, the driver immediately stepped on the brake.
In the figurative meaning, 'Bremse' is often used with the verbs 'sein' (to be) or 'wirken' (to act/function). Typical phrases are 'eine Bremse für etwas sein' (to be a brake on something) or 'als Bremse wirken' (to act as a brake).
Seine pessimistische Haltung war eine echte Bremse für das ganze Team.
His pessimistic attitude was a real brake on the whole team.
drive
'der Antrieb' and 'die Bremse' can be opposites because they act in different directions. Technically, an Antrieb sets a vehicle or machine in motion, while a Bremse slows the movement down or stops it. The contrast also works figuratively: an inner Antrieb helps a person become active. A Bremse is then something that hinders progress or development. Memory aid: der Antrieb moves something forward; die Bremse holds it back.

Vor der Kurve trat Sofia auf die Bremse, weil die Straße nass war.
Before the curve, Sofia stepped on the brake because the road was wet.
Der neue Antrieb macht das E-Bike am Berg deutlich stärker.
The new drive system makes the e-bike much more powerful on hills.