entzünden
to ignite
To set something on fire; to kindle a fire.
Er entzündete die Kerzen auf dem Geburtstagskuchen.
He ignited the candles on the birthday cake.

to ignite / to become inflamed / to spark
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to ignite
To set something on fire; to kindle a fire.
Er entzündete die Kerzen auf dem Geburtstagskuchen.
He ignited the candles on the birthday cake.

'Entzünden' is an inseparable verb. The prefix 'ent-' remains firmly attached to the verb stem 'zünden' in all tenses and sentence constructions.
Sie entzündete das Kaminfeuer mit einem einzigen Streichholz.
She ignited the fireplace with a single match.
You can recognize the meaning from the grammar and the object. The reflexive form 'sich entzünden' (to become inflamed) refers to a medical inflammation. The non-reflexive form with a concrete object means 'anzünden' (to light / to set on fire), and with an abstract object it means 'auslösen' (to trigger).
Sein Finger hat sich entzündet. (medizinisch)
His finger has become inflamed. (medical)
In the meaning of 'anzünden' (to light / to set on fire), the verb is combined with things that can burn. Typical objects are 'eine Kerze' (a candle), 'ein Feuer' (a fire), 'ein Streichholz' (a match), or 'ein Funke' (a spark).
Zum Geburtstag haben wir 30 Kerzen auf dem Kuchen entzündet.
For the birthday, we lit 30 candles on the cake.
In the medical sense, 'entzünden' is always used reflexively ('sich entzünden'). The subject of the sentence is the body part that is affected.
Nach dem Insektenstich hat sich mein Arm stark entzündet.
After the insect bite, my arm became badly inflamed.
In the figurative meaning, the objects are always abstract and often negative. Typical nouns are 'ein Streit' (an argument), 'eine Debatte' (a debate), 'ein Konflikt' (a conflict), or also strong feelings such as 'Leidenschaft' (passion).
Diese Entscheidung könnte einen neuen Konflikt zwischen den Parteien entzünden.
This decision could spark a new conflict between the parties.
to extinguish / delete
'löschen' and 'entzünden' are opposites when it comes to fire. 'entzünden' means to set something on fire or to start a fire. 'löschen' means to stop a fire again. Both words can be used with flames, candles, fireplaces, or fires, but they describe different directions. First you can 'eine Kerze entzünden' (light a candle), and later you can 'sie löschen' (put it out).

Das Kind entzündet die Kerze nur, weil die Mutter danebensteht.
The child lights the candle only because the mother is standing next to him.
Nach dem Essen löscht er die Kerzen auf dem Tisch.
After the meal, he puts out the candles on the table.