gemacht
artificial
Seeming artificial, affected, or not genuine.
Sein Lächeln wirkte gemacht und erreichte seine Augen nicht.
His smile seemed artificial and did not reach his eyes.

made
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artificial
Seeming artificial, affected, or not genuine.
Sein Lächeln wirkte gemacht und erreichte seine Augen nicht.
His smile seemed artificial and did not reach his eyes.

'Gemacht' (made) is the past participle of the verb 'machen' (to make/do). It is often used as an adjective to describe the result or manner of an action.
Diese Suppe ist wie selbst gemacht!
This soup is like homemade!
In this meaning, 'gemacht' (artificial) has a negative connotation and describes something as artificial or not genuine. It is often used for behavior or emotions that do not seem authentic.
Ihre Freundlichkeit wirkte aufgesetzt und gemacht.
Her friendliness seemed affected and artificial.
The idiom 'ein gemachter Mann' (a made man) or 'eine gemachte Frau' (a made woman) is a fixed expression. It describes a person who is so financially successful that they are provided for for the rest of their life.
Nach dem Lottogewinn war sie eine gemachte Frau.
After winning the lottery, she was a made woman.
In combination with an adverb, 'gemacht' (made) describes the quality or manner of execution. Typical patterns are 'gut gemacht' (well done/well made), 'schlecht gemacht' (badly done/badly made), or 'professionell gemacht' (professionally done/made).
Die Präsentation war sehr professionell gemacht.
The presentation was done very professionally.
natural / of course
'natürlich' and 'gemacht' describe a clear contrast here in appearance or behavior. 'Natürlich' means that someone seems genuine, relaxed, and unaffected. 'Gemacht' means that something seems artificial, affected, or not genuine. You use 'natürlich', for example, for a person who behaves normally and honestly. 'Gemacht' is more suitable when a smile, a voice, or a friendly manner does not seem genuine.

Sein Lächeln wirkte am Telefon etwas gemacht.
His smile seemed a bit fake over the phone.
Im Gespräch mit den Kunden bleibt Maria freundlich und natürlich.
When talking with customers, Maria remains friendly and natural.