
die Klamotte
clothes
A colloquial, often slightly derogatory expression for clothing. It is usually used in the plural ('Klamotten').
Ich muss dringend mal wieder neue Klamotten kaufen.
I really need to buy some new clothes again.
clothes / farce
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clothes
A colloquial, often slightly derogatory expression for clothing. It is usually used in the plural ('Klamotten').
Ich muss dringend mal wieder neue Klamotten kaufen.
I really need to buy some new clothes again.

farce
A colloquial term for an undemanding, often exaggerated and comic film or play.
Am Sonntagabend haben wir uns im Fernsehen eine alte Klamotte aus den 70ern angesehen.
On Sunday evening we watched an old 1970s farce on TV.
'Klamotte' and 'Klamotten' are very colloquial. In formal situations, for example in a business letter or job application, you should use 'Kleidung' (clothing) instead.
Für die Party habe ich mir ein paar coole Klamotten gekauft.
I bought myself some cool clothes for the party.
The meaning can often be recognized from the number form. The plural 'Klamotten' almost always refers to clothes. The singular 'die Klamotte', on the other hand, is often used for a silly film or play.
Ich muss noch meine Klamotten für den Urlaub packen.
I still have to pack my clothes for the vacation.
In connection with clothing, you often hear 'alte/neue Klamotten' (old/new clothes), 'sich in seine Klamotten werfen' (to throw on one's clothes / get dressed quickly), or 'seine Klamotten packen' (to pack one's things/clothes).
Wirf dich in deine besten Klamotten, wir gehen heute Abend schick aus!
Throw on your best clothes; we're going out somewhere fancy tonight!
garment
Both words can refer to a single item of clothing. However, Klamotte is colloquial and often sounds casual or slightly derogatory, while Kleidungsstück is neutral and factual. Kleidungsstück is appropriate in a normal description, whereas Klamotte may be more suitable for a casual evaluation.

Diese alte Klamotte ziehe ich nur noch zum Streichen der Wohnung an.
I only wear this old piece of clothing when I paint the apartment.
Dieses Kleidungsstück ist aus warmer Wolle und eignet sich gut für den Winter.
This garment is made of warm wool and is well suited for winter.