der Marker
marker
A thick felt-tip pen used to highlight passages of text (highlighter) or to write on various surfaces.
Bitte markiere die wichtigsten Abschnitte mit einem gelben Marker.
Please mark the most important sections with a yellow marker.

marker
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marker
A thick felt-tip pen used to highlight passages of text (highlighter) or to write on various surfaces.
Bitte markiere die wichtigsten Abschnitte mit einem gelben Marker.
Please mark the most important sections with a yellow marker.

'Marker' (marker) is closely related to the verb 'markieren' (to mark). A marker is therefore always something that serves to make a mark — whether with color, as a biological signal, or as a sign.
Ich markiere die wichtigen Termine im Kalender mit einem roten Marker.
I mark the important appointments in the calendar with a red marker.
The word 'Marker' (marker) is very often used in compound nouns that describe its function more precisely. Examples are 'Textmarker' (highlighter), 'Whiteboard-Marker' (whiteboard marker), or 'Tumormarker' (tumor marker).
Kannst du mir den Textmarker geben? Ich möchte diesen Satz hervorheben.
Can you give me the highlighter? I want to highlight this sentence.
The meaning as a biological indicator is purely technical language. You hear and read this word in the context of medicine, genetics, or biology.
Das Vorhandensein dieses Markers im Blut kann auf eine Infektion hindeuten.
The presence of this marker in the blood can indicate an infection.
sign / symbol
'das Zeichen' and 'der Marker' can both indicate something. 'das Zeichen' is the general term for a symbol, a marking, or an indication. 'der Marker' is more specific: it can be a marking in data, in a text, or on a playing field. In medicine and biology, it can also be a characteristic that indicates a condition or disease. The words are confused because a 'Marker' often functions like a 'Zeichen'. 'Zeichen' fits generally, while 'Marker' fits more in technical, scientific, or precisely marked contexts.

Die Ärztin erklärt, dass dieser Marker auf eine Entzündung hinweisen kann.
The doctor explains that this marker can indicate inflammation.
Neben dem Namen steht ein kleines Zeichen für neue Nachrichten.
Next to the name, there is a small symbol for new messages.