zweitgrößt
second-largest
Ranking second in an order based on size. Only one thing is larger.
Hamburg ist die zweitgrößte Stadt Deutschlands.
Hamburg is the second-largest city in Germany.

second-largest
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second-largest
Ranking second in an order based on size. Only one thing is larger.
Hamburg ist die zweitgrößte Stadt Deutschlands.
Hamburg is the second-largest city in Germany.

This adjective is made up of the ordinal number 'zweit-' (second) and the superlative 'größt-' (largest). This pattern is very productive and can be used for any kind of ranking, e.g. 'drittgrößte' (third-largest), 'viertwichtigste' (fourth-most important), 'fünftbeste' (fifth-best).
Das ist das drittbeliebteste Reiseziel der Deutschen.
That is the third-most popular travel destination among Germans.
'Zweitgrößt' (second-largest) is almost always used as an attributive adjective before a noun and usually appears with the definite article. It is declined like a normal superlative adjective.
Der Mount Everest ist der höchste Berg, der K2 ist der zweithöchste.
Mount Everest is the highest mountain; K2 is the second-highest.
The group to which the ranking refers is often indicated with the genitive or a 'von' construction.
Köln ist die viertgrößte Stadt Deutschlands.
Cologne is the fourth-largest city in Germany.