by no means
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by no means
Expresses a strong negation; under no circumstances, not in any case.
Du solltest dieses Medikament keinesfalls ohne ärztlichen Rat einnehmen.
You should by no means take this medication without medical advice.
The word is made up of 'keines' (genitive of 'kein') and 'Falls' (from 'der Fall'). So it literally means 'keines Falles' (in no case) and can be translated as 'in no case'.
Ich werde dir keinesfalls mein Auto leihen.
I will by no means lend you my car.
'Keinesfalls' (by no means) can stand in position 1 to strongly emphasize the negation. In this case, the verb follows directly after it (inversion). But it can also stand after the verb and the subject.
Keinesfalls solltest du diese E-Mail öffnen!
By no means should you open this email!
'Keinesfalls' (by no means) is a very strong and rather formal way of negating something. It expresses more emphasis than a simple 'nicht' (not).
Die vertraulichen Informationen dürfen keinesfalls an Dritte weitergegeben werden.
The confidential information must by no means be passed on to third parties.
never
'nie' and 'keinesfalls' can both negate something very strongly. 'nie' mainly says that something happens at no time. 'keinesfalls' means 'under no circumstances' and is especially useful for rules, warnings, or clear decisions. 'nie und nimmer' (never ever) is similarly strong to 'keinesfalls', but sounds more colloquial and more emotional. When it is about time, 'nie' is natural. When you clearly forbid or rule something out, 'keinesfalls' is more precise.
Morgen darfst du die wichtigen Unterlagen keinesfalls vergessen.
Tomorrow you must not forget the important documents under any circumstances.
Bei der Arbeit esse ich nie am Schreibtisch.
At work, I never eat at my desk.