anpacken
to tackle
To begin dealing with a task or problem decisively and energetically.
Statt nur zu reden, sollten wir die Sache jetzt endlich anpacken.
Instead of just talking, we should finally tackle the matter now.

to tackle / to grab
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to tackle
To begin dealing with a task or problem decisively and energetically.
Statt nur zu reden, sollten wir die Sache jetzt endlich anpacken.
Instead of just talking, we should finally tackle the matter now.

'Anpacken' (to tackle / to grab) is a separable verb. In a main clause, the prefix 'an' comes at the end. In a subordinate clause and in the infinitive with 'zu', the verb stays together.
Wir packen die Renovierung nächstes Wochenende an.
We are tackling the renovation next weekend.
You can recognize the meaning from the object: an abstract object ('Problem' (problem), 'Aufgabe' (task)) means 'to begin dealing with'. A concrete, physical object ('Koffer' (suitcase), 'Möbelstück' (piece of furniture)) means 'to grab'. The expression 'mit anpacken' means 'to pitch in/help'.
Lass uns die Gartenarbeit anpacken, bevor es regnet.
Let's tackle the gardening before it rains.
The construction 'mit anpacken' always means 'to help with physical work'. The 'mit' emphasizes the shared aspect.
Wenn alle mit anpacken, sind wir mit dem Aufbau schnell fertig.
If everyone pitches in, we'll finish setting it up quickly.
to help
'helfen' and 'anpacken' can both mean supporting someone with a task. 'helfen' is the more general word: you can help with advice, time, money, or work. 'anpacken' fits especially when someone actively joins in and does something practical. It often sounds more energetic than 'helfen'. When many people have to get something done together, it is natural to say: 'Alle packen mit an.' (Everyone pitches in.)

Beim Umzug haben alle Nachbarn mit angepackt.
During the move, all the neighbors pitched in.
Kannst du mir bitte helfen, die schweren Taschen ins Auto zu tragen?
Can you please help me carry the heavy bags to the car?