gefährdet
endangered
Being in a situation where danger or harm threatens; being exposed to a risk.
Durch den Klimawandel sind viele Tierarten stark gefährdet.
Because of climate change, many animal species are seriously endangered.

endangered / at risk
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endangered
Being in a situation where danger or harm threatens; being exposed to a risk.
Durch den Klimawandel sind viele Tierarten stark gefährdet.
Because of climate change, many animal species are seriously endangered.

'Gefährdet' (endangered/at risk) is the past participle of the verb 'gefährden' (to endanger). It is derived from the noun 'die Gefahr' (danger). The whole word family revolves around the topic of risk and danger.
Rauchen gefährdet die Gesundheit; Raucher sind daher stärker gefährdet.
Smoking endangers health; smokers are therefore more at risk.
In this general meaning, 'gefährdet' (endangered) is often used in nature conservation and species protection. A typical fixed expression is 'vom Aussterben gefährdet' (threatened with extinction). It can also be used for abstract things such as jobs or peace.
Der Panda ist eine vom Aussterben gefährdete Tierart.
The panda is a species threatened with extinction.
This meaning refers specifically to people in a difficult social environment. You can often recognize it from the combination with 'sozial' (socially) or when the topic is 'Jugendliche' (teenagers/young people) or 'Kinder' (children).
Der Verein bietet Hilfe für sozial gefährdete Familien an.
The association offers help for socially at-risk families.
sure / safe
'sicher' and 'gefährdet' are opposites here. 'sicher' means that someone or something is protected from danger or harm. 'gefährdet' means that there is a danger or that harm may be threatened. You use 'sicher' when the risk is low or controlled. 'gefährdet' fits when a person, animal, building, or situation is exposed to a risk.

Bei starkem Sturm sind alte Bäume besonders gefährdet.
In a strong storm, old trees are especially at risk.
Nach der Reparatur ist die Brücke wieder sicher.
After the repair, the bridge is safe again.