die Prognose
forecast
A prediction about the future development of something, based on data, analyses, or experience.
Die wirtschaftliche Prognose für das nächste Jahr ist positiv.
The economic forecast for next year is positive.

prognosis / forecast
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forecast
A prediction about the future development of something, based on data, analyses, or experience.
Die wirtschaftliche Prognose für das nächste Jahr ist positiv.
The economic forecast for next year is positive.

A prognosis or forecast is typically 'gestellt' (made/given) or 'abgegeben' (issued/given). Later, a prognosis can 'sich bestätigen' (be confirmed) or turn out to be wrong.
Experten stellen eine positive Prognose für die Wirtschaft.
Experts are making a positive forecast for the economy.
To evaluate a prognosis or forecast, adjectives such as 'gut' (good) or 'schlecht' (bad), 'positiv' (positive) or 'negativ' (negative), and 'optimistisch' (optimistic) or 'pessimistisch' (pessimistic) are often used.
Die erste Prognose war zu optimistisch und musste korrigiert werden.
The first forecast was too optimistic and had to be corrected.
To express what the prediction refers to, the preposition 'für' (for) with the accusative is usually used.
Die Prognose für das nächste Quartal sieht gut aus.
The forecast for the next quarter looks good.
You can recognize the medical meaning from the context. Words such as 'Arzt' (doctor), 'Patient' (patient), 'Krankheit' (illness), or 'Heilungschancen' (chances of recovery) clearly point to a medical prognosis.
Der Arzt gab dem Patienten eine vorsichtige Prognose.
The doctor gave the patient a cautious prognosis.
tip / prediction
'der Tipp' and 'die Prognose' can both say something about the future. A 'Tipp' is often more personal, less certain, and especially common in sports or betting. 'Die Prognose' sounds more objective and is more likely to be based on data, analyses, or experience, for example in weather, economics, or medicine. Learners may confuse the words because both can be a prediction. As a practical rule: for a personal assessment, you are more likely to say 'Tipp'; for a specialist or well-founded prediction, 'Prognose' is more appropriate.

Die Prognose zeigt, dass die Mieten in der Stadt weiter steigen könnten.
The forecast shows that rents in the city could continue to rise.
Mein Tipp für das Spiel heute Abend ist ein 2:1 für Dortmund.
My prediction for the match tonight is a 2-1 win for Dortmund.