ungeklärt
unresolved
Not yet solved, answered, or clarified; open or unclear.
Die Ursache des Unfalls ist bisher ungeklärt.
The cause of the accident is still unresolved.

unresolved / untreated
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unresolved
Not yet solved, answered, or clarified; open or unclear.
Die Ursache des Unfalls ist bisher ungeklärt.
The cause of the accident is still unresolved.

The word is made up of two parts: the prefix 'un-' (not) and 'geklärt', the past participle (Partizip II) of 'klären' (to clarify). 'Ungeklärt' (unresolved / untreated) therefore literally means 'not clarified' or 'not solved'.
Viele Fragen zu dem historischen Ereignis sind bis heute ungeklärt.
Many questions about the historical event remain unresolved to this day.
The context reveals the meaning: If people are talking about abstract things like a question, a case, or a cause, 'ungeklärt' (unresolved) means unsolved. If people are talking about liquids such as wastewater, it means 'not cleaned'.
Der Verbleib des Geldes ist weiterhin ungeklärt.
The whereabouts of the money remain unresolved.
In the meaning 'ungelöst' (unresolved), the word is often combined with nouns such as 'Frage' (question), 'Fall' (case), 'Mord' (murder), or 'Ursache' (cause). It describes a situation for which there is still no answer or solution.
Die Polizei ermittelt in einem bisher ungeklärten Fall.
The police are investigating a case that has so far remained unresolved.
The meaning 'nicht gereinigt' (not cleaned) is mainly used in technical or environmental contexts. The most common word in this context is 'ungeklärtes Abwasser' (untreated wastewater).
Die Fabrik wurde kritisiert, weil sie ungeklärte Industrieabwässer einleitete.
The factory was criticized because it discharged untreated industrial wastewater.
open
'offen' and 'ungeklärt' can both describe something that has not yet been decided or solved. 'offen' is more general and fits well with questions, items on a list, or decisions that are still pending. 'ungeklärt' puts more emphasis on the fact that the answer, cause, or solution is not yet known. That is why people often say 'eine offene Frage' (an open question), but 'die Ursache ist ungeklärt' (the cause is unresolved). Learners may confuse the words because both point to something unfinished. However, 'ungeklärt' sounds more like a problem that needs to be investigated or explained.

Nach dem Unfall ist die genaue Ursache noch ungeklärt.
After the accident, the exact cause is still unresolved.
Vor dem Urlaub ist noch offen, wer die Katze füttert.
Before the vacation, it is still open who will feed the cat.