aufräumen
to tidy up
To make a place neat and clean by putting things in their proper place.
Jeden Samstag muss ich mein Zimmer aufräumen.
Every Saturday I have to tidy up my room.

to tidy up / clear up
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to tidy up
To make a place neat and clean by putting things in their proper place.
Jeden Samstag muss ich mein Zimmer aufräumen.
Every Saturday I have to tidy up my room.

'Aufräumen' (to tidy up/clear up) is a separable verb. In a main clause, the prefix 'auf' goes to the end, while in a subordinate clause it remains attached to the verb. In the infinitive with 'zu', 'zu' goes in the middle: 'aufzuräumen'.
Wann räumst du endlich dein Zimmer auf?
When are you finally going to tidy up your room?
In the literal meaning, 'aufräumen' (to tidy up) is often combined with places or areas that are put in order. Typical objects are 'das Zimmer' (the room), 'die Wohnung' (the apartment), 'den Schreibtisch' (the desk), or 'die Küche' (the kitchen).
Bevor die Gäste kommen, müssen wir noch die Wohnung aufräumen.
Before the guests arrive, we still have to tidy up the apartment.
In the figurative meaning 'to eliminate prejudices', 'aufräumen' (to clear up) is always used with the preposition 'mit' and the dative. The structure is: 'mit etwas (Dativ) aufräumen'.
Dieser Dokumentarfilm räumt mit vielen Klischees auf.
This documentary clears up many clichés.
to do / make
'machen' and 'aufräumen' can both mean that a place is put back in order. However, 'machen' is very general and usually needs a more specific addition, for example 'das Zimmer sauber machen' (to clean the room). 'aufräumen' is more precise: things are put in their place so that a room is tidy. The words can be confused because both are used for housework. If the main point is tidiness, 'aufräumen' is the more suitable word. If it is about cleaning or getting something done in general, 'machen' can be more natural.

Nach dem Spielen räumt das Kind sein Zimmer auf.
After playing, the child tidies up his room.
Omar hat die Küche gemacht, weil später Gäste kommen.
Omar cleaned up the kitchen because guests are coming later.