
die Kehrtwende
reversal
A complete 180-degree change in a previous opinion, stance, or policy.
In der Debatte vollzog der Politiker eine überraschende Kehrtwende.
In the debate, the politician made a surprising reversal.
U-turn / reversal
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reversal
A complete 180-degree change in a previous opinion, stance, or policy.
In der Debatte vollzog der Politiker eine überraschende Kehrtwende.
In the debate, the politician made a surprising reversal.

U-turn
The physical act of turning around 180 degrees in order to go or drive in the opposite direction.
Der Fahrer machte auf der schmalen Straße eine gewagte Kehrtwende.
The driver made a daring U-turn on the narrow road.
'Kehrtwende' (U-turn/reversal) is a compound noun made from 'kehren' (to turn around) and 'Wende' (a turn, a change). The combination of the two words reinforces the meaning of a complete and often sudden 180-degree reversal.
Die Firma machte eine Kehrtwende in ihrer Strategie.
The company made a reversal in its strategy.
The word 'Kehrtwende' (U-turn/reversal) is very often combined with the verbs 'machen' (to make/do) or 'vollziehen' (to carry out, to make). 'Eine Kehrtwende vollziehen' is a somewhat more formal expression.
Der Zeuge vollzog vor Gericht eine Kehrtwende in seiner Aussage.
The witness made a reversal in his statement in court.
You can recognize the figurative meaning from an abstract context. When it is about politics, opinions, strategies, or decisions, it always means a change in stance.
Nach Protesten der Bürger vollzog die Regierung eine Kehrtwende in der Umweltpolitik.
After protests by citizens, the government made a reversal in environmental policy.
You can recognize the literal, physical meaning from the context of movement. Words like 'Auto' (car), 'Fahrer' (driver), 'Straße' (road), 'Weg' (path), or 'Schiff' (ship) indicate that someone or something is actually turning around.
Das Schiff machte im Hafen eine langsame Kehrtwende.
The ship made a slow U-turn in the harbor.
turning point / turn
Wende can generally refer to an important turning point or change without everything being reversed. Kehrtwende, on the other hand, explicitly means a complete reversal of a previous position or policy. Use Wende for a decisive change, and Kehrtwende for a clear reversal of an established course.

Die Regierung vollzog nach den Protesten eine Kehrtwende in ihrer bisherigen Politik.
After the protests, the government made a complete U-turn on its previous policy.
Die neue Vereinbarung war eine Wende in der bisherigen Politik.
The new agreement marked a turning point in the previous policy.